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Cholinergic Agonists and Cholinergic Antagonists

Horizontales
Cholinergic antagonist, antinicotinic, ganglion blocker Nn, starts with T
Direct acting, act upon Ach Receptors, muscarinic, choline ester, non selective muscarinic agonist, diagnostic test for asthma because upon inhalation causes a hyperreactiactive bronchoconstriction
Indirect acting irreversible AchE inhibitor, used as an antihelminthic (parasitic infections)
Cholinergic antagonist, antinicotinic, neuromuscular blocker Nm, depolarizing blocker,occupies the receptor and causes short depolarization but are slowly metabolized so they remain bound to the Nm receptor for a longer duration which blocks its reactivation, shorter acting
Indirect acting reversible AchE inhibitor, increases transmission at the neuromuscular junction, starts with p
Indirect acting reversible AchE inhibitor, Carbamates (intermediate half life), increases transmission at the neuromuscular junction, have a number of clinical applications
Direct acting, act upon Ach receptors, muscarinic, choline ester, Non selective muscarinic agonist, stimulant of the smooth muscle of the GI tract and the urinary bladder used for post operative abdominal distension and urinary retention
Indirect acting AchE inhibitor, short acting
Cholinergic antagonist, antinicotinic, neuromuscular blocker, Nm, competitive antagonist, prevents the opening of the channel when bound to the receptor, Longer acting
Indirect acting irreversible AchE inhibitor, used as a scabicide
Direct acting, acts upon Ach Receptors, muscarinic, alkaloid, used to treat dry mouth caused by sjogren's syndrome
Cholinergic antagonist, antimuscarinic, treatment of asthoma/COPD
Cholinergic antagonist, antimuscarinic, treats urinary incontinence
Direct acting, acts upon Ach Receptors, muscarinic, alkaloid, starts with m
Verticales
Direct acting, act upon Ach receptors, muscarinic, choline ester, not a good drug because it is non specific, poorly absorbed, and very rapidly hydrolyzed
Cholinergic antagonist, antinicotinic, ganglion blocker Nn, starts with H
Cholinergic antagonist, antimuscarinic, M3 selective
Cholinergic antagonist, antimuscarinic, used to treat motion sickness
Cholinergic antagonist, antimuscarinic, non-selective, used clinically to induce mydriasis, decrease secretions during induction of anesthesia, counteract mushroom poisoning, counteract organophosphate intoxication/exposure
Indirect acting irreversible AchE inhibitor, organophosphates (long lasting effect)
Cholinergic antagonist, antimuscarinic, M1 selective
Direct Acting, act upon Ach Receptors, choline ester, starts with C