type of acid that is used in histotechnology both as a fixative ingredient and as a stain.
______ solutions have equal osmotic pressure resulting in little disruption of the cell.
Widely used as a fixative for GI biopsy specimens.
When surrounded by a ____ solution, the water leaves the cell and the cell shrink.
type of fixative that chemically combines with the tissue proteins that change the shape of the tissue.
Fixative reagent that goes well with tissue to be Trichrome stained.
This type of pigment will appear in tissue when the pH level is below 6.0.
the destruction of cells or tissues by their own enzymes, occurs from delayed fixation.
A rare physical method of fixation. Removes moisture from tissue.
This type of fixative solution can surround tissue samples in a container indefinitely.
an artificial structure or tissue alteration on a prepared microscopic slide as a result of poor fixation.
is a substance used to bind dyes on tissue samples. Used for intensifying stains in cells or tissue preparations.
Most widely used type of fixative in histology.
Type of fixative solution that can cause cell swelling and possible rupturing of its membrane.
Only osmium tetroxide and _____ acid will fix lipids and make them insoluble during tissue processing.
A heterogeneous group of substances that contain enough natural color to be visible without any further staining.
Verticales
Type of transport solution used routinely for mailing kidney biopsies.
The rate of _____ and mode of action determines the minimum length of time that a fixative needs to act on the tissue.
The _____ fixatives act by creating a gel that makes penetration by the subsequent solutions difficult.
type of fixative which ingredients are primarily acetone and ethyl/methyl alcohol. These fixatives are very flammable too.
is the change in the 3D structure of the macromolecules within the tissue. Generally, applies to proteins and nucleic acids.
Refers to the number of particles in a solution. Very important for ultra-structural studies.
is the decay/breakdown of tissue through the means of bacteria.
_____ fixatives act on tissue without chemically combining with it. Dissociate bound water molecules from tissue protein groups.
Fixative ______ needs to be 15-20 times greater than the tissue volume for adequate fixation to occur.
ensures that tissue is adequately preserved to provide an image of the tissue as it appeared within the living body at the time of tissue removal.
Type of fixative that creates a network of proteins within the tissue that allows solutions to easily penetrate.
This type of solution is the preferred fixative for carbohydrates (glycogens).
Fixative reagent ingredient utilized to fix brain tissue for diagnosis of rabies.
Fixative factor that influences the reactivity of the fixative.
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