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Pituitary Disorders

Horizontales
Associated with Normal Intelligence, GH deficiency, abnormal stature
Greater than 1cm, impingement of optic chiasm
Positive loop feedback, excess oxytocin
Can cause Diabetes Inspidus, approach to remove tumor
Treatment of choice Diabetes Insipidus
Craving for ice water, large volume polyuria
And infertility in men 2/2 prolactinoma
Amenorrhea, galactorrhea
Breastfeeding, Trust/Empathy, Role in patients with Autism
Acromegaly
Before closure of epiphyses
Verticales
Hyponatremia, decreased plasma osmolality
Central pontine, potential risk associated with rapid correction of SIADH
Dopamine agonist, Prolactinomas, decrease tumor size
Posterior Pituitary Hormone: conservation of free water
Oral dopamine agonist of choice, reduction of IGF-1
HTN, cardiomegaly, Insulin Resistance
deficiency of ACTH, decreased cortisol
Abnormal curvature of the spine, Dwarfism
MCC by stroke, meningitis, CNS