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IXINITY Product Knowledge

Horizontales
There is a validated ______ step process to reduce CHO proteins.
This type of tolerance is used to eliminate an inhibitor
Keep the IXINITY vial in the carton and protect from ________.
What percentage of the general population has the Thr148 allele?
IXINITY data shows 31% of patients being _______ free after 18 months.
Factor IX is a purified protein of 415 of these.
With IXINITY, peak factor levels are achieved within how many minutes?
There are no drug-drug or drug- _______ interactions with IXINITY
IXINITY is indicated for age _______ and older.
This is a not-for-profit organization that provides services and contract pricing for federally funded HTCs that either have, or are seeking to have, pharmacy programs under Section 340B of the PHS Act.
AUC is a function of the _______ of the drug in the blood plasma.
Verticales
The four steps of the coagulation cascade lead to this
What represents the rate that factor is cleared from plasma?
An HTC is typically a federally recognized comprehensive hemophilia treatment center with what type of team?
The clinical trials included a total of 9,641 ______ of IXINITY
Zero of these were needed during surgery in the IXINITY clinical data.
There were no human or these other proteins added to IXINITY during manufacturing.
Do not do this with IXINITY
Genetically engineered technology.
When patients in a clinical study switched to IXINITY, no ________ developed.
The IXINITY manufacturing process is designed for purity and ______.
The most common adverse drug reaction observed with IXINITY.
IXINITY data shows Zero ________ AsBR.
The lower the clearance, the ______ a volume of factor remains in the blood.