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Chapter 12 Crossword -

Horizontales
A class of psychoactive drugs that act on GABA receptors.
An approach to drug synthesis used for focused lead optimization studies.
Primarily used to treat psychotic disorders such as schizophrenia
Chemical synthetic method that makes it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process.
A lash-like appendage that protrudes from the cell body of certain bacteria and eukaryotic cells
Used topically topically to treat burns, the skin condition psoriasis and even acne.
A medication of the beta blocker class
A dense, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid
Chemical messenger which plays an essential role in stimulating blood vessels to open wider, thereby allowing more blood to flow to various tissues.
A drug that is effective against vomiting and nausea
A nitrogenous compound involved in the inflammatory response and has a central role as a mediator of itching
Constitutes about 80% of the catecholamine content in the brain. This hormone is generally given to Parkinson's patients in the form of L-Dopa
Binds to microtubular proteins and arrests mitosis at the metaphase by disrupting mitotic spindle formation
A family of protease enzymes playing essential roles in programmed cell death
Verticales
A catecholamine that functions in the brain and body as a hormone and neurotransmitter. The name is from Latin roots meaning "at/alongside the kidneys"
A protein whose endogenous ligand has not yet been identified.
A widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism
An antiplatelet drug for intravenous application
A method for attaching a probe or substrate of interest to a specific biomolecule, a process called bioconjugation
Aselective beta blocker used in the emergency treatment of cardiac arrhythmias.
Gamma Amino Benzoic Acid
Endogenous compounds with benzodiazepine like effects.
A tricyclic antidepressant (TCA)
Trade name = Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer
An antifungal medicine which inhibits a demethylase enzyme
The occurrence and development of events by chance in a happy or beneficial way
Calculated versus experimentally determined log P values
A chemical agent that causes severe burning of the skin, eyes and respiratory tract.
A stomach acid reducer that is used to treat and prevent certain types of stomach ulcer.
A class of antidepressants named for their structure which contains three rings
Medicinal approach that is also called also called phytomedicine or phytotherapy