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Medicinal Chemistry Chapter 11 - Pharmacokinetics

Horizontales
A route of administration for drugs via an injection into the spinal canal
A chemotherapy medication given by injection into a vein.
An antioxidant capable of preventing damage to important cellular components
Administered into a muscle:
a process of Transdermal drug delivery by use of a voltage gradient on the skin
Administered into a vein
The second phase of drug metabolism is conjugation , which is a Phase I metabolite joining to another compound.
The proportion of a drug or other substance which enters the circulation and so is able to have an active effect.
A liposome is a spherical vesicle having at least one lipid bilayer.
A bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption
Commonly used to treat blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent stroke
Mixture prepared according to a particular formula
A rule of thumb to if a compound has chemical properties and physical properties that would make it a likely orally active drug in humans
A small, extrachromosomal DNA molecule within a cell
The microscopic structural and functional unit of the kidney
A local anesthetic of the amino amide type.
Verticales
An antibiotic used for the treatment of tuberculosis.
Study of how your DNA affects the way you respond to drugs
Enzymes that incorporate one hydroxyl group into substrates in many metabolic pathways.
A protein that contains a heme prosthetic group
An opiate used to treat pain, coughing, and diarrhea
A relationship applied to buffers; relates the proportion of base to acid to pH
Provide controllable drug administration via a osmotically driven minipump
A dark-green-to-yellowish-brown fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine.
Gastrointestinal tract
An angiotensin-converting enzyme (ACE) inhibitor class drug used to treat high blood pressure, heart failure, and after heart attacks; Transported by a dipeptide transporter
The major artery carrying blood from the heart
Also called water channels
Used to treat Parkinson's Disease; transported by the phenylalanine transporter
An opioid pain medication used to treat moderate to moderately severe pain.