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Chapter 10 -Miscellaneous Drug Targets

Horizontales
The systematic study of all glycan structures of a given cell type or organism
Taxoid characterized by its high tolerability, antitumor efficacy, ability to overcome multidrug resistance, and oral bioavailabilty
A molecule or molecular structure, such as may be present at the outside of a pathogen
Hormone to which pegaptanib binds
A drug that competitively inhibits the interaction between the two cancer-linked nuclear proteins
A class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders and related illnesses to serotonin deficiencies
a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds.
An antibody fragment which inhibit blood clotting following angioplasty procedures
The protein shell of a virus, enclosing its genetic material
the general classification for carbohydrates covalently linked with other chemical species such as proteins, peptides, lipids and saccharides.
an antifungal medication used for serious fungal infections and leishmaniasis
Also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer.
oligonucleotide or peptide molecules that bind to a specific target molecule.
An example of a drug that binds to tubulin and prevents it polymerization
Sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, breast cancer, lung cancer
An intravenous treatment for complicated skin infections, Its target is a biosynthetic building block
A chemical nerve cells produce. It sends signals between your nerve cells.
TIROFIBAN
Verticales
Linear peptide with 15 amino acids.
Proxac
A class of antimicrobial peptides found in the African clawed frog- contains 23 -residues
Drugs which fool transport proteins into accepting a drug
Promote microtubule assembly and inhibit microtubule disassembly.
A procedure, characterized by the repetition of successive steps consisting of selection (binding, partition, and elution), amplification and conditioning that helps researchers find an aptamer to bind to virtually any protein target
A medication for the reversal of neuromuscular blockade induced by rocuronium and vecuronium. in general anaesthesia.
Constitutes about 80% of the catecholamine content in the brain
a naturally occurring dodecadepsipeptide used in the transport of potassium and as an antibiotic
An antibiotic protein synthesis inhibitor which causes premature chain termination during translation
Proteins which contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
a multifunctional intermediate calcium-binding messenger protein
a multibranched polysaccharide of glucose that serves as a form of energy storage in animals, fungi, and bacteria
Anti-obesity drug which inhibits the reuptake of serotonin, noradrenaline, and dopamine
An antibody used as an immunosuppressant in kidney transplants
a major component of the eukaryotic cytoskeleton
a biomolecule that is soluble in nonpolar solvents