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Viral Infections of the CNS

Horizontales
In rabies, the _____ matter of the brain is targeted (polioencephalomyelitis)
Canine distemper virus comes from this group of RNA viruses.
Teschen and Talfan are examples of diseases that can cause this condition in pigs usually after weaning, causing a meningoencephalomyelitis along the entire neuraxis of the gray matter. This often leads to motor neuron necrosis as well as ganglioneuritis.
In FIP, you might find this kind of inflammation along the cerebral vessels around the ventricular system, often involving the ependymal lining. There are also often neutrophils involved.
This cell type is the tropism for Equine herpes myeloencephalitis virus, which ultimately damages the white matter of the spinal cord and brainstem through necrotizing vasculitis and white matter ischemia and infarction.
This is NOT a finding of Equine Arboviral Encephalitis
This mutated coronavirus creates a fibrinous exudation in the CSF, making it more of a gel. It also causes immune-mediated vasculitis.
This cell type is a unique finding of Eastern Equine Encephalitis
The perivascular cuffing seen in a viral infections of the CNS usually involves this broad class of cells.
Verticales
CAE causes this type of demyelination by directly affecting oligodendrocytes.
This virus causes leukoencephalomyelitis that directly damages oligodendrocytes impacting the white matter of the brain.
A common outcome of rabies virus given the way that it utilizes axonal transport and passes through the ganglia.
This equine arbovirus affects both endothelial cells and neurons, often leading to hemorrhage in the brainstem.
This is the location where negri bodies of rabies virus will specifically be found in herbivores.
The subacute demyelinating encephalitis form of canine distemper (which is the more common form of CVD seen) specifically targets this cell type, leading to periventricular lesions of the white matter and secondary loss of oligodendrocytes.
This structure is the center of the inflammation in poliomyelitis of pigs.
CAE is this type of virus that infects monocytes and macrophages, causing extensive demyelination by an immune-mediated process.