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Antigen-Antibody Reactions

Horizontales
Estimated to contribute half of the total bond strength
Measure of antibody present
Attraction of two oppositely charged groups
Ability of an antibody to react with a particular antigen and no other antigen
Optimum concentration of Ab and Ag present for a visible reaction to occur
Excess of anibody
Excess of antigen leading to no lattice formation
Verticales
Additive strength of all bonds in multivalent antigen and antibodies
Weak but many bonds formed
Lack of specificity
Binding strength of one paratope to one epitope
Also known as antigenic determinant
Interaction between electronic clouds