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Mitochondria 1

Horizontales
promotes mitochondrial biogenesis via transcriptional regulation of TFAM, ATP50, NRF1, NRF2 genes
Disruptions in these processes implicated in a neurodegenerative disease
one of the most powerful signals for PGC 1- alpha
A type of enzyme used by Cancer cells to regulate ROS levels
Medication can restore the mitochondrial oxidant/antioxidant balance
functions as an antioxidant in cells, lowering the levels of ROS by reducing the levels of intracellular iron
A process needed to create new mitochondria
A type of cell having more than 2000 mitochondria
Shuttles fatty acids to the mitochondria
A mechanism used by chemotherapeutics drugs
Verticales
A raw material for ATP molecule
A process helps mitigate stress by mixing the contents of partially damaged mitochondria as a form of complementation
A pathway deregulated in diseases as cancer and type 2 diabetes
A hormone that overrides the hypothalamus signal and instructs sugar burning
master transcriptional regulator of mitochondrial biogenesis
Types of cells that are sensitized by fasting/FMDs
best lipid measure of incident atherosclerotic cardiovascular disease risk