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BREAST CANCER CROSSWORD

Horizontales
Model to assess risk of carrying the BRCA mutation
Surgeon who pioneered Radical Mastectomy
D-Care trial evaluated this drug for its role in improving DFS
Minimum number of months to have received Endocrine therapy before interruption to attempt pregnancy in the PROMISE trial
ADC with a monoclonal antibody linked with SN-38
Online tool from UK to estimate risk of recurrence and benefit of addition of therapies
Gene associated with increased risk of breast cancer, mucocutanoeus pigmented lesion and hamrtamatous polyps
Verticales
Reversible pan ERBB inhibitor that binds to both EGFR and Her2
Trial which compared 1 year was 2 years of adjuvant trastuzumab
Most common AE with Alpelisib apart from increased blood sugars
Number of genes analysed by the Mamma print Assay
To call it Her2 Amplified, The Her2 copy number/ cell should be atleast