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Food and Drug Interations

Horizontales
These preparations are small, offering easier drug uptake at the cellular level, allowing for more efficient drug delivery
This effect decreases drug bioavailability
Food-drug interactions are most commonly seen with this fruit
This effect occurs when food consumption increases drug bioavailability
In this reaction, a patient presents with headache, nausea/vomiting, chest pain, vertigo, thirst and weakness in the setting of a positive blood ethanol level and history of metronidazole use
Alcohol and tylenol taken together can lead to this toxicity
True or false - separating timing of ingestion of grapefruit from medication ingestion prevents the drug interaction
These interactions occur when food alters a drugs clinical effect on the body
This interacts with linezolid, isoniazid and monoamine oxidase inhibitors and can be avoided by eating mostly fresh foods that are cooked and eaten the same day
Fruit that contain this may increase iron absorption by creating a more acidic GI environment to help the iron dissolve adequately for absorption
These interactions occur with delivery devices or enteral feeding products
These formulations help the drug release further down the GI tract, allowing for increased absorption
Verticales
This food group commonly decreases absorption of many drugs such as ciprofloxacin, levothyroxine and tetracyclines
A diet high in this antagonizes warfarin's therapeutic effect, leading to an increased risk of clots
This drug should be taken first thing in the morning on an empty stomach at least 30 minutes before food intake or at night 3-4 hours after the last meal
This antibiotic is oil-based and can can adhere to feeding tubes, leading to decreased absorption
These interactions occur when food affects movement of drugs throughout the body
Found in leafy greens, blueberries, carrot juice, tuna, spaghetti sauce and prunes
A sudden decrease in this McDonald's favorite can lead to lithium toxicity
Enteral nutrition should be held 1 hour before or 2 hours after administering this type of drug to prevent decreased absorption
These enzymes account for 70-80% of drug metabolism