A sudden rise in serum levels of this (more than 25% of baseline value) is a good indicator of allograft rejection. _______________________
Rejection characterized by lymphocytic infiltration of the tubules, interstitium, and sometimes the arterial intima. (Hint: its an abbreviation) _______________________
Type of donor that has a higher rejection rate. _______________________
Depletion of this is a a leading cause in early and late post transplant rejection. _______________________
Patients with renal transplants require this type of team approach during post-transplant care. _______________________
New onset, or worsening of this should raise suspicion for rejection. _______________________
The treatment of choice in patients with end-stage renal disease or severe chronic kidney disease as it improves the quality of life and has better survival advantages compared to dialysis. (Hint: 2 words) ______________________________________________
This, along with awareness, are key factors for the prevention of allograft rejection. (Hint: 2 words) ______________________________________________
The standard way to detect a renal allograft rejection. _______________________
Finding an increased amount of this in the urine is an indicator of rejection. _______________________
Rejection that usually demonstrates evidence of circulating donor-specific alloantibodies and immunological evidence of antibody-mediated injuries to the kidney. (Hint: its an abbreviation) _______________________
Verticales
Inflammation with specific pathologic changes in the allograft, due to the recipient’s immune system recognizing the non-self antigen in the allograft, with or without dysfunction of the allograft. (Hint: 2 words) ______________________________________________
Rejection that happens minutes after transplant, and is related to the preformed antibody or ABO incompatibility; this is rarely seen now due to the very sensitive cross-match tests performed before the transplant. _______________________
Rejection that can happen any time after transplant, usually within days to weeks after transplant. _______________________
This is one of the critical risk factors for the development of rejection. _______________________
Graft survival has improved with the use of more advanced and potent _______________________ agents for induction and maintenance therapy.
The principal cells that recognize the allograft. (Hint: 2 words w/o the hyphen)
This depends on the type of rejection and managed with more immunosuppression and optimizing baseline immunosuppressive regimen post rejection. _______________________
Rejection that usually develops more than three months post-transplant. _______________________
Age group of recipient that has a higher rejection rate. _______________________
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