A class of anticoagulants that act rapidly, are taken orally, and require no monitoring.
An important clotting factor that is a target of many recently developed orally active anticoagulants
A P450 isozyme with 2 relatively common loss of function genetic alleles that reduce the effectiveness of a commonly used antiplatelet drug
A heterogeneous group of anionic mucopolysaccharides that are given parenterally to produce a rapid onset anticoagulant effect
Another word for platelet that most people outside of medicine would not recognize
Can be used to save lives and limbs, and which patients become quite attached to. A natural source of hirudin. Also a term describing a person who sponges on others.
An antiplatelet that is combined with a P2Y12 inhibitor in the treatment of patients undergoing PCI and placement of a coronary stent. Can also be used to treat headaches.
A blood glycoprotein that sticks to collagen and binds to GP1b receptors, initiating platelet activation
A word that describes the most common appearance of venous thrombi
A type of myocardial infarction where fibrinolytics are not used because of lack of evidence of benefit vs risk
A 3rd generation P2Y12 inhibitor having a very short half life, and which is given by iv infusion. Used in situations where a rapid onset of effect is needed.
A word describing the most common appearance of arterial thrombi.
Released by platelets and constricts blood vessels, producing local vascular stasis
Verticales
This drug is taken orally, and specifically inhibits thrombin
A term used to describe clopidogrel
The antidote for overdose by an orally acting anticoagulant that has a slow onset of action, many drug interactions, requires a consistent diet, and requires close monitoring.
An mTOR inhibitor used in drug-eluting stents which reduces the number of macrophages in the vessel wall that secrete inflammatory cytokines and growth factors that contribute to restenosis
A highly basic protein that binds to and neutralizes the action of a commonly used anticoagulant.
A commonly used 2nd generation inhibitor of P2Y12 ADP receptors
A drug given as a single iv bolus to treat a STEMI when timely access to a PCI capable facility is not possible
The most common side effect of anticoagulants
A prescription drug that is a common component of DAPT, and for which there is no specific reversal agent if a patient starts to bleed
A side effect of a commonly used anticoagulant that produces clots and significantly reduces platelet counts
Historically, this agent made cows sick, killed rats, and provided the Wisconsin Alumni Research Foundation some major moola (no reference to cows intended).
The initial 5 letters of a platelet receptor that binds fibrinogen, and is involved in a final common pathway for platelet aggregation
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