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Crucigrama Sopa de Letras Hoja de Trabajo
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Rare Disease Week 2022

Horizontales
A disorder that affects the spleen and is common in India and Japan. Main symptom is spleen enlargement.
Symptoms include jerky movements of the arms and legs, happy disposition, and unprovoked episodes of laughter and smiling.
The name of this syndrome is the acronym of its 4 symptoms. May also include seizures.
Partial deletion of the short arm of chromosome 5 with a characteristic high-pitched, shrill cry that resembles the mewing of a cat.
This is a rare disease in children less than one year old and can cause sudden infant death.
Caused by not getting enough vitamin C, more common in underdeveloped countries, can lead to gum disease, anemia, and skin hemorrhages.
Verticales
A cardiovascular disorder caused by mutation in the SCN5A gene that encodes for the sodium channels in the heart. Symptoms include irregular heartbeat, trouble breathing, fainting, and can lead to sudden death.
A type of lung infection caused by a yeast-like fungus called Pneumocytis jirovecii. Treatment is antibiotics such as Bactrim.
Build up of fat called phytanic acid in blood plasma and tissue. Phytanic acid is a type of fatty acid which is derived by bacterial fermentation of green plants or algae.
This disease affects the insulating material in our brain, due to the mutation in a gene called GFAP